
In the recent issue of nature Scientists from CCMB, Hyderabad, India and Harvard have pursued a new genome wide survey of human variation for the population in India. This is the featured article in the cover of the magazine. They catagorize the population into two groups, which emerged from two genetically divergent ancestors, viz., Ancestoral North Indians (ANI) and Ancestoral South Indians (ASI).
They observe that while ANI is genetically close to Middle Easteners, Central Asians, and Europeans, on the other hand ASI have distinct genetic signature and is not close to ANI or East Asians, asserting that they are of indigeneous kind of the subcontinent.
The data was collected from 25 diverse groups across India.
They conclude that Allele frequency difference is higher in India than in Europe. They further predict that there will be an excess of recessive diseases in India. The only way out is to screen and map genetically!
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